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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLE
All Species:
7.58
Human Site:
S27
Identified Species:
18.52
UniProt:
Q07864
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07864
NP_006222.2
2286
261518
S27
S
R
D
D
G
A
T
S
S
V
S
A
L
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543348
2273
260734
R27
S
S
V
S
A
L
K
R
L
E
R
S
Q
W
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVF7
2283
262009
S27
S
R
D
D
G
P
S
S
S
V
S
A
L
K
R
Rat
Rattus norvegicus
NP_001100622
1515
174729
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233985
2277
260654
K27
G
P
A
L
S
A
L
K
R
L
E
R
S
Q
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121995
2284
262166
L27
Q
Q
D
D
A
S
A
L
S
A
V
K
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524462
2236
256683
F27
N
R
T
E
G
D
D
F
F
N
E
A
G
Y
R
Honey Bee
Apis mellifera
XP_393171
2183
252634
S28
Q
N
Q
E
G
N
A
S
G
D
A
S
G
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328167
2221
254636
E29
L
M
R
T
A
E
E
E
L
E
S
K
L
G
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21951
2222
255653
Y30
Y
N
T
L
S
N
N
Y
A
L
S
A
Q
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.7
N.A.
90.5
60.7
N.A.
N.A.
83.7
N.A.
80
N.A.
55.2
54.6
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
94.6
N.A.
95
63.5
N.A.
N.A.
92
N.A.
90.2
N.A.
71.9
71.5
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
86.6
0
N.A.
N.A.
13.3
N.A.
20
N.A.
26.6
20
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
93.3
0
N.A.
N.A.
26.6
N.A.
33.3
N.A.
40
40
N.A.
N.A.
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
40.5
N.A.
Protein Similarity:
62.7
N.A.
N.A.
N.A.
60.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
30
20
20
0
10
10
10
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
30
0
10
10
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
20
0
10
10
10
0
20
20
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
40
0
0
0
10
0
0
0
20
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
20
0
20
0
% K
% Leu:
10
0
0
20
0
10
10
10
20
20
0
0
30
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
20
0
0
0
20
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
20
10
10
0
0
0
0
0
0
0
0
0
20
20
0
% Q
% Arg:
0
30
10
0
0
0
0
10
10
0
10
10
10
0
50
% R
% Ser:
30
10
0
10
20
10
10
30
30
0
40
20
10
10
0
% S
% Thr:
0
0
20
10
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
20
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _